Recent studies on ursolic acid and its biological and pharmacological activity

نویسندگان

  • Sook Young Lee
  • Yong Joo Kim
  • Sun Ok Chung
  • Sang Un Park
چکیده

1 Regional Innovation Center for Dental Science and Engineering, Chosun University, 309 Pilmun-daero, Dong-gu, Gwangju, 501-759, Korea 2 Department of Biosystems Machinery Engineering, Chungnam National University, 99 Daehak-ro, Yuseong-gu, Daejeon, 305-764, Korea 3 Department of Crop Science, Chungnam National University, 99 Daehak-ro, Yuseong-gu, Daejeon, 305-764, Korea * Corresponding author: E-mail: [email protected], Phone: +82-42-822-2631, Fax: +82-42-822-2631

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Cytotoxic effect of hydro-alcoholic extract of pomegranate (Punica granatum L.) flowers and isolated ursolic acid on B16f10 melanoma cells

Background: Melanoma is the most serious form of skin cancer and it has the highest rate of growth among different types of cancers. Ursolic acid (UA), a natural pentacyclic triterpenoid, is a major bioactive compound in several traditional medicinal plants including pomegranate (Punica granatum L.) flower. UA has very important biological and pharmacological functions. Objective: In this study...

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Letter to the editor: RECENT STUDIES ON URSOLIC ACID AND ITS BIOLOGICAL AND PHARMACOLOGICAL ACTIVITY

1 Regional Innovation Center for Dental Science and Engineering, Chosun University, 309 Pilmun-daero, Dong-gu, Gwangju, 501-759, Korea 2 Department of Biosystems Machinery Engineering, Chungnam National University, 99 Daehak-ro, Yuseong-gu, Daejeon, 305-764, Korea 3 Department of Crop Science, Chungnam National University, 99 Daehak-ro, Yuseong-gu, Daejeon, 305-764, Korea * Corresponding author...

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We and other studies have elucidated single molecules that can attenuate aging and extend longevity. Indeed, these molecules could prevent age-associated diseases simultaneously and probably extending healthy-life spans. In this review, we discuss recent advances, controversies, opportunities and challenges surrounding ursolic acid (UA) in relationship with aging. In this regard, UA also known ...

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عنوان ژورنال:

دوره 15  شماره 

صفحات  -

تاریخ انتشار 2016